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KMID : 1132720040020040167
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Genomics & Informatics
2004 Volume.2 No. 4 p.167 ~ p.173
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The Atom of Evolution
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Phak Jong-Hwa
Bolser Dan M.
Park Dae-Ui
Cho Yoo-Bok
Yoon Kie-Suk
Lee Se-Min
Gong Sung-Sam
Jang In-Soo
Park Chang-Bum
Huston Maryana
Choi Hwan-Ho
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Abstract
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The main mechanism of evolution is that biological entities change, are selected, and reproduce. We propose a different concept in terms of the main agent or atom of evolution: in the biological world, not an individual object, but its interactive network is the fundamental unit of evolution. The interaction network is composed of interaction pairs of information objects that have order information. This indicates a paradigm shift from 3D biological objects to an abstract network of information
entities as the primary agent of evolution. It forces us to change our views about how organisms evolve and therefore the methods we use to analyze evolution.
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KEYWORD
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interactome, comparative interactomics, network biology, interfacemome, biological information objects
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